1) Pick's disease is the old name for the disorder frontotemporal lobar degeneration (FTLD) and in particular the behavioural variant frontotemporal dementia (FTD). Certainly a number of patient support groups continue to use the name "Pick's disease" in their titles. This confusion has led many neurologists to suggest other names for FTLD. The most prominent is perhaps Kertesz' suggestion of the term "Pick Complex" to encompass not only the clinical subtypes of FTLD, but also the overlapping syndromes of corticobasal degeneration and progressive supranuclear palsy.
2) Neurologists use the term "Pick's disease" to mean specifically one of the pathological subtypes of FTLD. The pathological hallmark of Pick's disease are Pick bodies. These are spherical cytoplasmic inclusions found within neurons in affected portions of the brain.[1] They cause neurons to swell, taking on a "ballooned" appearance.
2 comments:
do you have it?
Yes, he does! And the degeneration has migrated to his back and knees.
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